Ferg Lab

Research

Mosquito Surveillance in the Maritimes

Climate change is mosquito-friendly in the Maritimes and we can expect new species to arrive as their ranges expand. We are currently updating the catalogue of mosquito species within the Maritime provinces with intensive sampling of larvae and adults in Nova Scotia, New Brunswick, and PEI. Complementary to traditional sampling methods, we are also using eDNA and community science to detect invasive species of mosquitoes. We are also tracking the prevalence of WNV, EEEV, and California Serogroup viruses in our mosquitoes. Check out @AcadiaMosquitoTeam on social media for updates during the field season!

Overwintering biology of ticks and mosquitoes

Winter is an important season for ectotherms, including vectors, which sets the stage for their ability to transmit disease in the growing season. We are interested in how winter and winter climate change impact the range expansion and abundance of ticks and mosquitoes. We use simulated overwintering conditions, as well as field exposures, to explore winter behaviour and physiology. In ticks, we are particularly interested in the role of the bacteria, Borrelia burgdorferi, in overwintering success. We also explore the role of pathogens in driving overwintering mortality.

Immunity and infection in changing environments

As our environment continues to warm, what will happen to disease dynamics in insects? The insect immune system is sensitive to temperature, but warmer is not always better. Plus, pathogen growth and virulence is also in the equation. To understand how insects will cope with disease with climate change, we study variation in the immune system in response to changing temperatures.

Impacts of microplastics on invertebrate physiology

Microplastics are ubiquitous in the environment and can have deleterious effects on animals. Currently we are exploring how microplastic ingestion impacts cold tolerance in mosquito larvae.

Publications

Cold-induced immune activation in chill-susceptible insects

MI El-Saadi, HA MacMillan, LV Ferguson Current Opinion in Insect Science, 101054 2023


Cold wars and climate change: how host-pathogen interactions at lowtemperatures shape ectothermsuccess in changing environments

LV Ferguson, A El Nabbout, SA Adamo INTEGRATIVE AND COMPARATIVE BIOLOGY 62, S93-S93 2023

From perplexing to predictive: are we ready to forecast insect disease susceptibility in a warming world?

LV Ferguson, SA Adamo Journal of Experimental Biology 226 (4), jeb244911 2023


Balsam fir (Abies balsamea) needles and their essential oil kill overwintering ticks (Ixodes scapularis) at cold temperatures

SA Adamo, A El Nabbout, LV Ferguson, JS Zbarsky, N Faraone Scientific reports 12 (1), 12999 2022

Changes in the microbiome and associated host tissue structure in the blue mussel (Mytilus edulis) following exposure to polystyrene microparticles

LV Ferguson, B Hewins, W Harding, E MacDonald, G Gibson Canadian Journal of Zoology 100 (11), 719-731 2022


Applied ecoimmunology: using immunological tools to improve conservation efforts in a changing world

Michel EB Ohmer, David Costantini, Gábor Á Czirják, Cynthia J Downs, Laura V Ferguson, Andy Flies, Craig E Franklin, Ahab N Kayigwe, Sarah Knutie, Corinne L Richards-Zawacki, Rebecca L Cramp Conservation Physiology 9 (1), coab074 2021

Detection of heliothine sex pheromone components in the Australian budworm moth, Helicoverpa punctigera: electrophysiology, neuroanatomy, and behavior

K Cloonan, AR Rizzato, L Ferguson, NK Hillier Journal of Comparative Physiology A 206, 939-950 2020


Thermal variability and plasticity drive the outcome of a host-pathogen interaction

LV Ferguson, BJ Sinclair The American Naturalist 195 (4), 603-615 2020

Effects of Environmentally-Relevant Levels of Microplastics on Tissue Structure in Mytilus edulis (Blue Mussels)

B Hewins, A Rideout, W Harding, E Macdonald, L Ferguson, G Gibson INTEGRATIVE AND COMPARATIVE BIOLOGY 59, E334-E334 2019

Sugar intake interacts with temperature to influence reproduction and immunity in adult Culex pipiens mosquitoes

LV Ferguson, NH Beckett, M-C French, MJ Campbell, TG Smith, SA Adamo Canadian Journal of Zoology 97 (5), 424-428 2019

Seasonal shifts in the insect gut microbiome are concurrent with changes in cold tolerance and immunity

Laura V Ferguson, Pranav Dhakal, Jacqueline E Lebenzon, David E Heinrichs, Carol Bucking, Brent J Sinclair Functional ecology 32 (10), 2357-2368 2018

Eco-immunology in the cold: the role of immunity in shaping the overwintering survival of ectotherms

LV Ferguson, R Kortet, BJ Sinclair Journal of Experimental Biology 221 (13), jeb163873 2018

Insect immunity varies idiosyncratically during overwintering

LV Ferguson, BJ Sinclair Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, 327 (5), 222-234 2017

Insect immunity varies idiosyncratically during overwintering

LV Ferguson, BJ Sinclair Journal of Experimental Zoology Part A: Ecological and Integrative Physiology 327, 222-234 2017

Thermal Biology of Insect Immunity and Host-microbe Interactions

LV Ferguson The University of Western Ontario (Canada) 2017

Does cold activate the Drosophila melanogaster immune system?

G Salehipour-Shirazi, LV Ferguson, BJ Sinclair Journal of insect physiology 96, 29-34 2017


Metabolic differences between fast/slow life histories of damselflies (Odonata: Zygoptera)

TJ Dann, L Ferguson, R Jakobs, GP Closs, BJ Sinclair 2016 International Congress of Entomology 2016

Reproductive arrest and stress resistance in winter-acclimated Drosophila suzukii

J Toxopeus, R Jakobs, LV Ferguson, TD Gariepy, BJ Sinclair Journal of insect physiology 89, 37-51 2016

Can we predict the effects of multiple stressors on insects in a changing climate?

S Kaunisto, LV Ferguson, BJ Sinclair Current opinion in insect science 17, 55-61 2016

Paradoxical acclimation responses in the thermal performance of insect immunity

LV Ferguson, DE Heinrichs, BJ Sinclair Oecologia 181, 77-85 2016

An invitation to measure insect cold tolerance: methods, approaches, and workflow

Brent J Sinclair, Litza E Coello Alvarado, Laura V Ferguson Journal of Thermal Biology, 53, 180-197 2015


Parallel ionoregulatory adjustments underlie phenotypic plasticity and evolution of Drosophila cold tolerance

HA MacMillan, LV Ferguson, A Nicolai, A Donini, JF Staples, BJ Sinclair Journal of Experimental Biology 218 (3), 423-432 2015

Cold hardiness and deacclimation of overwintering Papilio zelicaon pupae

Caroline M Williams, Annegret Nicolai, Laura V Ferguson, Mark A Bernards, Jessica J Hellmann, Brent J Sinclair Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 178, 51-58 2014


Influence of Hepatozoon parasites on host-seeking and host-choice behaviour of the mosquitoes Culex territans and Culex pipiens

LV Ferguson, NK Hillier, TG Smith International Journal for Parasitology: Parasites and Wildlife 2, 69-76 2013

Cross-tolerance and cross-talk in the cold: relating low temperatures to desiccation and immune stress in insects

BJ Sinclair, LV Ferguson, G Salehipour-Shirazi, HA MacMillan Integrative and comparative biology 53 (4), 545-556 2013

Factors determining the in vitro emergence of sexual stages of Hepatozoon clamatae from erythrocytes of the Green Frog (Rana clamitans)

MJ Trites, LV Ferguson, CT Ogbuah, CM Dickson, TG Smith Canadian journal of zoology 91 (4), 219-226 2013